A Comparative Genomics Approach to Understanding Transmissible Cancer in Tasmanian Devils
-
Altmetric Citations
Deakin, Janine; Belov, Katherine
Description
A fatal contagious cancer is driving an entire species to extinction. Comparative genomics will unravel the origin and evolution of devil facial tumor disease (DFTD). The DFTD allograft arose from a Schwann cell in a female Tasmanian devil more than 15 years ago; since then, the tumor has passed through at least 100,000 hosts, evolving and mutating along the way. Tumor genome sequencing and molecular cytogenetic technologies now allow direct comparisons of candidate genes involved in...[Show more]
Collections | ANU Research Publications |
---|---|
Date published: | 2012 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/64833 |
Source: | Annual Review of Genomics and Human Genetics |
DOI: | 10.1146/annurev-genom-090711-163852 |
Download
File | Description | Size | Format | Image |
---|---|---|---|---|
01_Deakin_A_Comparative_Genomics_2012.pdf | 574.32 kB | Adobe PDF | Request a copy |
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 19 May 2020/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator