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Molecular characterisation of the CD79a and CD79b subunits of the B cell receptor complex in the gray short-tailed opossum (Monodelphis domestica) and tammar wallaby (Macropus eugenii): Delayed B cell immunocompetence in marsupial neonates

Duncan, L; Webster, K; Gupta, V.; Nair, S.; Deane, Elizabeth


The B cell receptor (BCR) is a multiprotein complex that is pivotal to antigen recognition and signal transduction in B cells. It consists of an antigen binding component, membrane Ig (mIg), non-covalently associated with the signaling component, a disulphide-linked heterodimer of CD79a and CD79b. In this study, the gene and corresponding cDNA for CD79a and CD79b in the gray short-tailed opossum, as well as the cDNA sequences for CD79a and CD79b in the tammar wallaby, are described. Many of the...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Veterinary Immunology and Immunopathology
DOI: 10.1016/j.vetimm.2010.03.013


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