Predicting channel function from channel structure using Brownian dynamics simulations
Chung, Shin-Ho; Kuyucak, Serdar
1. The transport process of ions across the potassium channel is studied using computer simulations. The shape of the model channel corresponds closely to that deduced from crystallography. 2. We first give an intuitive account of how the motion of ions experiencing an applied electric force and interacting with a dielectric boundary and charge residues on the channel wall can be simulated accurately by using a powerful supercomputer. 3. We then show how some of the salient features of ion...[Show more]
|Collections||ANU Research Publications|
|Source:||Clinical and Experimental Pharmacology and Physiology|
|01_Chung_Predicting_channel_function_2001.pdf||312.52 kB||Adobe PDF||Request a copy|
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.
Updated: 17 November 2022/ Responsible Officer: University Librarian/ Page Contact: Library Systems & Web Coordinator