Skip navigation
Skip navigation

NASH is an inflammatory disorder: Pathogenic, prognostic and therapeutic implications

Farrell, Geoffrey; Van Rooyen, Derrick; Gan, Lay; Chitturi, Shivakumar

Description

While non-alcoholic fatty liver disease (NAFLD) is highly prevalent (15% to 45%) in modern societies, only 10% to 25% of cases develop hepatic fibrosis leading to cirrhosis, end-stage liver disease or hepatocellular carcinoma. Apart from pre-existing fibrosis, the strongest predictor of fibrotic progression in NAFLD is steatohepatitis or non-alcoholic steatohepatitis (NASH). The critical features other than steatosis are hepatocellular degeneration (ballooning, Mallory hyaline) and mixed infl...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/64186
Source: Gut and Liver
DOI: 10.5009/gnl.2012.6.2.149

Download

File Description SizeFormat Image
01_Farrell_NASH_is_an_inflammatory_2012.pdf1.99 MBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  20 July 2017/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator