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Conserved functional surface of antimammalian scorpion β-toxins

Chen, Rong; Chung, Shin-Ho

Description

Scorpion β-toxins bind to the voltage-sensing domain of voltage-gated sodium (NaV) channels and trap the voltage-sensing domain in the activated state. Two structurally similar β-toxins from scorpions, Css4 and Cn2, selectively target different subtypes

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/64164
Source: Journal of Physical Chemistry B
DOI: 10.1021/jp300127j

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