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The effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: Role of endogenous TLR ligands

Uaesoontrachoon, Kitipong; Cha, Hee-Jae; Ampong, Beryl; Sali, A; Vandermeulen, J; Wei, B; Creeden, B; Huynh, Tony; Quinn, James; Tatem, Kathleen S; Rayavarapu, S

Description

An absence of dysferlin leads to activation of innate immune receptors such as Toll-like receptors (TLRs) and skeletal muscle inflammation. Myeloid differentiation primary response gene 88 (MyD88) is a key mediator of TLR-dependent innate immune signallin

dc.contributor.authorUaesoontrachoon, Kitipong
dc.contributor.authorCha, Hee-Jae
dc.contributor.authorAmpong, Beryl
dc.contributor.authorSali, A
dc.contributor.authorVandermeulen, J
dc.contributor.authorWei, B
dc.contributor.authorCreeden, B
dc.contributor.authorHuynh, Tony
dc.contributor.authorQuinn, James
dc.contributor.authorTatem, Kathleen S
dc.contributor.authorRayavarapu, S
dc.date.accessioned2015-12-10T23:12:32Z
dc.identifier.issn0022-3417
dc.identifier.urihttp://hdl.handle.net/1885/64027
dc.description.abstractAn absence of dysferlin leads to activation of innate immune receptors such as Toll-like receptors (TLRs) and skeletal muscle inflammation. Myeloid differentiation primary response gene 88 (MyD88) is a key mediator of TLR-dependent innate immune signallin
dc.publisherJohn Wiley & Sons Inc
dc.sourceJournal of Pathology
dc.subjectKeywords: dysferlin; myeloid differentiation factor 88; osteopontin; single stranded RNA; toll like receptor; toll like receptor 1; toll like receptor 13; toll like receptor 2; toll like receptor 4; toll like receptor 5; toll like receptor 6; toll like receptor 7; degeneration; dysferlin; inflammation; osteopontin; regeneration; single-stranded RNA; Toll-like receptor
dc.titleThe effects of MyD88 deficiency on disease phenotype in dysferlin-deficient A/J mice: Role of endogenous TLR ligands
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume231
dc.date.issued2013
local.identifier.absfor220400 - RELIGION AND RELIGIOUS TRADITIONS
local.identifier.ariespublicationU3488905xPUB878
local.type.statusPublished Version
local.contributor.affiliationUaesoontrachoon, Kitipong, Children’s National Medical Center
local.contributor.affiliationCha, Hee-Jae, Research Center for Genetic Medicine
local.contributor.affiliationAmpong, Beryl, Research Center for Genetic Medicine
local.contributor.affiliationSali, A, Research Center for Genetic Medicine
local.contributor.affiliationVandermeulen, J, Research Center for Genetic Medicine
local.contributor.affiliationWei, B, Research Center for Genetic Medicine
local.contributor.affiliationCreeden, B, Research Center for Genetic Medicine
local.contributor.affiliationHuynh, Tony, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationQuinn, James, Children’s National Medical Center
local.contributor.affiliationTatem, Kathleen S, Children’s National Medical Center
local.contributor.affiliationRayavarapu, S, Research Center for Genetic Medicine
local.description.embargo2037-12-31
local.bibliographicCitation.issue2
local.bibliographicCitation.startpage199
local.bibliographicCitation.lastpage209
local.identifier.doi10.1002/path.4207
dc.date.updated2016-02-24T10:16:03Z
local.identifier.scopusID2-s2.0-84883897292
CollectionsANU Research Publications

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