Microcystins (MCs) are highly toxic, non-ribosomal cyclic peptides produced by cyanobacteria. A wide range of environmental factors are known to affect MC production, yet the roles these factors play in MC metabolism are poorly understood. In this study a physiological role for sulfur in MC synthesis is proposed. Rates of amino acid and MC-LR production were determined from N-limited chemostat grown cells of the toxic cyanobacterium Microcystis aeruginosa MASH-01A19. Cluster analysis of these...[Show more]
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