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Structure-Activity Relationships of Phenylpropanoids as Antifeedants for the Pine Weevil Hylobius abietis

Bohman, Bjorn; Nordlander, G.; Nordenhem, H.; Sunnerheim, K.; Borg-Karlson, A.-K.; Unelius, C.R.


Ethyl cinnamate has been isolated from the bark of Pinus contorta in the search for antifeedants for the pine weevil, Hylobius abietis. Based on this lead compound, a number of structurally related compounds were synthesized and tested. The usability of the Topliss scheme, a flow diagram previously used in numerous structure-activity relationship (SAR) studies, was evaluated in an attempt to find the most potent antifeedants. The scheme was initially followed stepwise; subsequently, all...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Chemical Ecology
DOI: 10.1007/s10886-008-9435-1


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