Myelopoiesis related to perinatal spleen
Adult murine spleen is known to have a major role in the development of dendritic cell (DC) subsets, including conventional DC and plasmacytoid DC. In this lab, long-term cultures (LTCs) established from murine spleen support continuous production of novel dendritic-like cells, termed LTC-DC. An in vivo equivalent subset also exists in spleen, namely L-DC. As co-cultures using LTC-derived splenic stroma support the outgrowth of L-DC from spleen and bone marrow sources, it is likely that spleen...[Show more]
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|Source:||Immunology and Cell Biology|
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|02_Hinton_Myelopoiesis_related_to_2010.pdf||516.64 kB||Adobe PDF||Request a copy|
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