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Cat's whiskers tea (orthosiphon stamineus) extract inhibits growth of colon tumor in nude mice and angiogenesis in endothelial cells via suppressing VEGFR phosphorylation

Ahamed, Mohamed B. Khadeer; Aisha, Abdalrahim F.A.; Nasser, Zeyad D.; Siddiqui, Jamshed M.; Ismail, Z.; Omari, S.M.S.; Majid, A.M.S. Abdul; Parish, Christopher

Description

Cat's whiskers (Orthosiphon stamineus) is commonly used as Java tea to treat kidney stones including a variety of angiogenesis-dependent diseases such as tumorous edema, rheumatism, diabetic blindness, and obesity. In the present study, antitumor potential of standardized 50% ethanol extract of O. stamineus leaves (EOS) was evaluated against colorectal tumor in athymic mice and antiangiogenic efficacy of EOS was investigated in human umbilical vein endothelial cells (HUVEC). EOS at 100 mg/kg...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/63598
Source: Nutrition and Cancer
DOI: 10.1080/01635581.2012.630160

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