The dengue virus NS2B-NS3 protease retains the closed conformation in the complex with BPTI
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Chen, Wan-Na; Loscha, Karin; Nitsche, Christoph; Graham, Bim; Otting, Gottfried
Description
The C-terminal β-hairpin of NS2B (NS2Bc) in the dengue virus NS2B-NS3 protease is required for full enzymatic activity. In crystal structures without inhibitor and in the complex with bovine pancreatic trypsin inhibitor (BPTI), NS2Bc is displaced from th
Collections | ANU Research Publications |
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Date published: | 2014 |
Type: | Journal article |
URI: | http://hdl.handle.net/1885/63472 |
Source: | FEBS Letters |
DOI: | 10.1016/j.febslet.2014.05.018 |
Access Rights: | Open Access |
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File | Description | Size | Format | Image |
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FEBSLett2014_588_2206.pdf | 2.24 MB | Adobe PDF |
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