Identification and validation of a gene causing cross-resistance between insecticide classes in Anopheles gambiae from Ghana
In the last decade there have been marked reductions in malaria incidence in sub-Saharan Africa. Sustaining these reductions will rely upon insecticides to control the mosquito malaria vectors. We report that in the primary African malaria vector, Anopheles gambiae sensu stricto, a single enzyme, CYP6M2, confers resistance to two classes of insecticide. This is unique evidence in a disease vector of cross-resistance associated with a single metabolic gene that simultaneously reduces the...[Show more]
|Collections||ANU Research Publications|
|Source:||PNAS - Proceedings of the National Academy of Sciences of the United States of America|
|Access Rights:||Open Access|
|01_Mitchell_Identification_and_validation_2012.pdf||766.72 kB||Adobe PDF|
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