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A model for amorphous aggregation processes

Stranks, Samuel; Ecroyd, Heath; Van Sluyter, Steven; Waters, Elizabeth; Carver, John; von Smekal, Lorenz


The amorphous aggregation of proteins is associated with many phenomena, ranging from the formation of protein wine haze to the development of cataract in the eye lens and the precipitation of recombinant proteins during their expression and purification. While much literature exists describing models for linear protein aggregation, such as amyloid fibril formation, there are few reports of models which address amorphous aggregation. Here, we propose a model to describe the amorphous...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Physical Review E
DOI: 10.1103/PhysRevE.80.051907


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