Insights into the biophysical properties of GABA A ion channels: Modulation of ion permeation by drugs and protein interactions
Tierney, Mary (Louise)
The fundamental properties of ion channels assure their selectivity for a particular ion, its rapid permeation through a central pore and that such electrical activity is modulated by factors that control the opening and closing (gating) of the channel. All cell types possess ion channels and their regulated flux of ions across the membrane play critical roles in all steps of life. An ion channel does not act alone to control cell excitability but rather forms part of larger protein complexes....[Show more]
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