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Glutamic acid residues in the C-terminal extension of small heat shock protein 25 are critical for structural and functional integrity

Morris, Amie; Treweek, Teresa; Aquilina, John Andrew; Carver, John; Walker, Mark

Description

Small heat shock proteins (sHsps) are intracellular molecular chaperones that prevent the aggregation and precipitation of partially folded and destabilized proteins. sHsps comprise an evolutionarily conserved region of 80-100 amino acids, denoted the α-

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/63172
Source: The FEBS Journal
DOI: 10.1111/j.1742-4658.2008.06719.x

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