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Dissociation from the Oligomeric State Is the Rate-limiting Step in Fibril Formation by K-Casein

Ecroyd, Heath; Koudelka, Tomas; Thorn, Davic C.; Williams, Danielle M.; Devlin, Glyn; Hoffmann, Peter; Carver, John


Amyloid fibrils are aggregated and precipitated forms of protein in which the protein exists in highly ordered, long, unbranching threadlike formations that are stable and resistant to degradation by proteases. Fibril formation is an ordered process that

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M709928200


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