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Implantation of functionalized thermally gelling xyloglucan hydrogel within the brain: associated neurite infiltration and inflammatory response

Nisbet, David; Rodda, AE; Horne, M; Forsythe, John S.; Finkelstein, D I


To develop neural tissue engineering strategies that are useful for repairing damaged neural pathways in the central nervous system, it is essential to control and optimise neurone and neurite interactions with functional scaffolds. In this study, the suitability of thermally gelling xyloglucan hydrogels, along with xyloglucan-graft-poly-d-lysine (PDL) hydrogels, was assessed through their implantation within the caudate putamen of adult rats. The ability of the hydrogel scaffolds to encourage...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Tissue Engineering Part A: Tissue Engineering
DOI: 10.1089/ten.tea.2009.0677


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