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The genome as a life-history character: why rate of molecular evolution varies between mammal species

Bromham, Lindell

Description

DNA sequences evolve at different rates in different species. This rate variation has been most closely examined in mammals, revealing a large number of characteristics that can shape the rate of molecular evolution. Many of these traits are part of the mammalian life-history continuum: species with small body size, rapid generation turnover, high fecundity and short lifespans tend to have faster rates of molecular evolution. In addition, rate of molecular evolution in mammals might be...[Show more]

dc.contributor.authorBromham, Lindell
dc.date.accessioned2015-12-10T23:08:00Z
dc.identifier.issn0962-8436
dc.identifier.urihttp://hdl.handle.net/1885/63109
dc.description.abstractDNA sequences evolve at different rates in different species. This rate variation has been most closely examined in mammals, revealing a large number of characteristics that can shape the rate of molecular evolution. Many of these traits are part of the mammalian life-history continuum: species with small body size, rapid generation turnover, high fecundity and short lifespans tend to have faster rates of molecular evolution. In addition, rate of molecular evolution in mammals might be influenced by behaviour (such as mating system), ecological factors (such as range restriction) and evolutionary history (such as diversification rate). I discuss the evidence for these patterns of rate variation, and the possible explanations of these correlations. I also consider the impact of these systematic patterns of rate variation on the reliability of the molecular date estimates that have been used to suggest a Cretaceous radiation of modern mammals, before the final extinction of the dinosaurs.
dc.publisherRoyal Society of London
dc.sourcePhilosophical Transactions of the Royal Society of London Series B
dc.subjectKeywords: adaptive radiation; body size; Cretaceous; evolutionary biology; fecundity; generation time; genomics; life history trait; longevity; mammal; molecular analysis; mutation; reproductive strategy; animal; article; genetics; genome; longevity; mammal; molecu Generation time; Longevity; Metabolic rate; Molecular clock; Mutation; Substitution
dc.titleThe genome as a life-history character: why rate of molecular evolution varies between mammal species
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume366
dc.date.issued2011
local.identifier.absfor060409 - Molecular Evolution
local.identifier.ariespublicationu9511635xPUB770
local.type.statusPublished Version
local.contributor.affiliationBromham, Lindell, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage2503
local.bibliographicCitation.lastpage2513
local.identifier.doi10.1098/rstb.2011.0014
local.identifier.absseo970106 - Expanding Knowledge in the Biological Sciences
dc.date.updated2016-02-24T12:08:28Z
local.identifier.scopusID2-s2.0-79961055146
local.identifier.thomsonID000293338700004
CollectionsANU Research Publications

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