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A randomized, double-blind, placebo-controlled trial of safety and efficacy of combined praziquantel and artemether treatment for acute schistosomiasis japonica in China

Hou, Xun-Ya; McManus, Donald P; Gray, Darren; Balen, Julie; Luo, Xin-Song; He, Yongkang; Ellis, Magda; Williams, Gail; Li, Yue-Sheng


Objective: To evaluate the safety and efficacy of combining artemether (AM) and praziquantel (PZQ) in different regimens for treating acute schistosomiasis japonica. Methods: We undertook a randomized, double-blind, placebo-controlled trial within four specialized schistosomiasis hospitals in the Dongting Lake region, Hunan province, China, between May 2003 and December 2005. Study participants were randomized into one of four treatment regimes: group A received 60 mg/kg PZQ + 6 mg/kg AM; group...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Bulletin of the World Health Organization
DOI: 10.2471/BLT.08.053041


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