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Brain plasticity, memory and neurological disorders: an epigenetic perspective

Lockett, Gabrielle; Wilkes (previously Baglow), Fiona; Maleszka, Ryszard

Description

Epigenomic settings control gene regulation in both developing and postmitotic tissue, whereas abnormal regulation of epigenomic settings has been implicated in many developmental and neurological disorders. Evidence is emerging for the roles of epigenetic mechanisms in the mature nervous system, in the dynamic processes of learning and memory. The discovery of the involvement of DNA methylation and histone acetylation and methylation in neuronal processing provides a possible answer to the...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/62593
Source: NeuroReport
DOI: 10.1097/WNR.0b013e32833e9288

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