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Gallic acid is the major component of grape seed extract that inhibits amyloid fibril formation

Liu, Yanqin; Pukala, Tara; Musgrave, Ian F.; Williams, Danielle M.; Dehle, Francis C.; Carver, John


Many protein misfolding diseases, for example, Alzheimer's, Parkinson's and Huntington's, are characterised by the accumulation of protein aggregates in an amyloid fibrillar form. Natural products which inhibit fibril formation are a promising avenue to e

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Bioorganic and Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2013.09.071


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