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Replication asynchrony and differential condensation of X chromosomes in female platypus (Ornithorhynchus anatinus)

Ho, Kristen K K; Deakin, Janine; Wright, Megan L; Graves, Jennifer; Grutzner, Frank

Description

A common theme in the evolution of sex chromosomes is the massive loss of genes on the sex-specific chromosome (Y or W), leading to a gene imbalance between males (XY) and females (XX) in a male heterogametic species, or between ZZ and ZW in a female heterogametic species. Different mechanisms have evolved to compensate for this difference in dosage of X-borne genes between sexes. In therian mammals, one of the X chromosomes is inactivated, whereas bird dosage compensation is partial and...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/62533
Source: Reproduction, Fertility and Development
DOI: 10.1071/RD09099

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