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Unravelling the evolutionary origins of X chromosome inactivation in mammals: insights from marsupials and monotremes

Deakin, Janine; Chaumeil, Julie; Hore, Tim; Graves, Jennifer

Description

Determining the evolutionary origin of X inactivation mechanisms in mammals requires knowledge of features of X inactivation across all three major mammal lineages; monotremes, marsupials and eutherians. In the past, research into X inactivation in marsupials and monotremes lagged far behind the major advances made in understanding the mechanisms of X inactivation in human and mouse. Fragmentary knowledge of the genic content and sequence of marsupial and monotreme X chromosomes has been...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
URI: http://hdl.handle.net/1885/62465
Source: Chromosome Research
DOI: 10.1007/s10577-009-9058-6

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