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Identification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans

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Vella, Peter; Miraula, Manfredi; Phelan, Emer; Leung, Eleanor W W; Ely, Fernanda; Ollis, David; McGeary, Ross Peter; Schenk, Gerhard; Mitic, Natasa

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Metallo-β-lactamases (MBLs) are a family of metalloenzymes that are capable of hydrolyzing β-lactam antibiotics and are an important means by which bacterial pathogens use to inactivate antibiotics. A database search of the available amino acid sequence

dc.contributor.authorVella, Peter
dc.contributor.authorMiraula, Manfredi
dc.contributor.authorPhelan, Emer
dc.contributor.authorLeung, Eleanor W W
dc.contributor.authorEly, Fernanda
dc.contributor.authorOllis, David
dc.contributor.authorMcGeary, Ross Peter
dc.contributor.authorSchenk, Gerhard
dc.contributor.authorMitic, Natasa
dc.date.accessioned2015-12-10T23:04:31Z
dc.identifier.issn0949-8257
dc.identifier.urihttp://hdl.handle.net/1885/62409
dc.description.abstractMetallo-β-lactamases (MBLs) are a family of metalloenzymes that are capable of hydrolyzing β-lactam antibiotics and are an important means by which bacterial pathogens use to inactivate antibiotics. A database search of the available amino acid sequence
dc.publisherSpringer
dc.sourceJournal of Biological Inorganic Chemistry
dc.subjectKeywords: ampicillin; biapenem; cefalotin; cefmetazole; cefoxitin; ceftazidime; cefuroxime; cephalosporin; imipenem; latamoxef; meropenem; metallo beta lactamase; penicillin G; piperacillin; amino acid sequence; amino acid substitution; antibiotic resistance; artic Antibiotics resistance; Binuclear metallohydrolases; Infectious disease; Metallo-ß-lactamases; Sequence homology
dc.titleIdentification and characterization of an unusual metallo-β-lactamase from Serratia proteamaculans
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume18
dc.date.issued2013
local.identifier.absfor039999 - Chemical Sciences not elsewhere classified
local.identifier.ariespublicationu4005981xPUB696
local.type.statusPublished Version
local.contributor.affiliationVella, Peter, University of Queensland
local.contributor.affiliationMiraula, Manfredi, National University of Ireland
local.contributor.affiliationPhelan, Emer, National University of Ireland
local.contributor.affiliationLeung, Eleanor W W, University of Queensland
local.contributor.affiliationEly, Fernanda, University of Queensland
local.contributor.affiliationOllis, David, College of Physical and Mathematical Sciences, ANU
local.contributor.affiliationMcGeary, Ross Peter, University of Queensland
local.contributor.affiliationSchenk, Gerhard, University of Queensland
local.contributor.affiliationMitic, Natasa, National University of Ireland-Maynooth
local.description.embargo2037-12-31
local.bibliographicCitation.issue7
local.bibliographicCitation.startpage855
local.bibliographicCitation.lastpage863
local.identifier.doi10.1007/s00775-013-1035-z
local.identifier.absseo970103 - Expanding Knowledge in the Chemical Sciences
dc.date.updated2016-02-24T10:25:53Z
local.identifier.scopusID2-s2.0-84885650988
local.identifier.thomsonID000324636200012
CollectionsANU Research Publications

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