Synthesis, structural characterisation, and preliminary evaluation of non-indolin-2-one-based angiogenesis inhibitors related to sunitinib (Sutent®)
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Sudta, Pichit; Kirk, Nicholas; Bezos, Anna; Gurlica, Anthony; Mitchell, Rhys; Weber, Thomas; Willis, Anthony; Prabpai, Samran; Kongsaeree, Palangpon; Suksamrarn, Sunit; Kelso, Michael; Parish, Christopher
Description
The indolin-2-one fused-ring system and the 2,4-dimethylpyrrole unit represent key structural motifs in the anticancer drug sunitinib (Sutent®) and predecessor angiogenesis inhibitors that have undergone anticancer clinical trials (e.g. semaxanib, SU5416
| Collections | ANU Research Publications |
|---|---|
| Date published: | 2013 |
| Type: | Journal article |
| URI: | http://hdl.handle.net/1885/62321 |
| Source: | Australian Journal of Chemistry |
| DOI: | 10.1071/CH13219 |
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| File | Description | Size | Format | Image |
|---|---|---|---|---|
| 01_Sudta_Synthesis,_structural_2013.pdf | 653.3 kB | Adobe PDF | Request a copy |
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