MEK, ERK, and p90RSK are present in mitotic tubulin in Swiss 3T3 cells - A role for the MAP kinase pathway in regulating mitotic exit
The mitogen-activated protein (MAP) kinase pathway has been implicated in cell cycle control for some time. Several reports have suggested a role for this pathway in growth factor stimulation of DNA synthesis, while other reports have proposed a role in the transition of cells through mitosis. Here, we have examined the potential involvement of the extracellular signal-related kinase (ERK)1/2 MAP kinases, their upstream regulators, and downstream effectors in the regulation of mitosis....[Show more]
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