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New systemic treatment options for metastatic renal-cell carcinoma in the era of targeted therapies

Tan, Thean Hsiang; PRANAVAN, Ganesalingam; Haxihimolla, Hodo; Yip, Desmond


Advances in understanding the biology and genetics of renal-cell carcinomas have led to the development of novel targeted therapies for the treatment of metastatic renal-cell cancer. Previously the systemic approaches were limited to cytokine therapies that were modest in their clinical benefits and at the expense of significant toxicities. Investigational treatments with allogeneic bone marrow transplantation were equally toxic and resulted in significant morbidity and mortality. The...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
Source: Asia-Pacific Journal of Clinical Oncology
DOI: 10.1111/j.1743-7563.2010.01277.x


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