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Monitoring the interaction between β2-microglobulin and the molecular chaperone αB-crystallin by NMR and mass spectrometry

Esposito, Gennaro; Garvey, Megan; Alverdi, Vera; Pettirossi, Fabio; Corazza, Alessandra; Fogolari, Federico; Polano, Maurizio; Mangione, P. Patrizia; Giorgetti, Sofia; Stoppini, Monica; Rekas, Agata; Bellotti, Vittorio; Heck, Albert J. R.; Carver, John


The interaction at neutral pH between wild-type and a variant form (R3A) of the amyloid fibril-forming protein β2-microglobulin (β2m) and the molecular chaperone αB-crystallin was investigated by thioflavin T fluorescence, NMR spectroscopy, and mass sp

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Journal of Biological Chemistry
DOI: 10.1074/jbc.M112.448639
Access Rights: Open Access


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