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Proofreading exonuclease on a tether: the complex between the E. coli DNA polymerase III subunits α, ε, θ and β reveals a highly flexible arrangement of the proofreading domain

Ozawa, Kiyoshi; Horan, Nicholas P; Robinson, Andrew; Yagi, Hiromasa; Hill, Flynn R; Jergic, Slobodan; Xu, Zhi-Qiang; Loscha, Karin; Li, Nan; Tehei, Moeava; Oakley, Aaron; Dixon, Nicholas Edward; Otting, Gottfried; Huber, Thomas


A complex of the three (αεθ) core subunits and the β2 sliding clamp is responsible for DNA synthesis by Pol III, the Escherichia coli chromosomal DNA replicase. The 1.7 Å crystal structure of a complex between the PHP domain of α (polymerase) and th

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Nucleic Acids Research
DOI: 10.1093/nar/gkt162
Access Rights: Open Access


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