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A direct proofreader-clamp interaction stabilizes the Pol III replicase in the polymerization mode

Jergic, Slobodan; Horan, Nicholas P; Elshenawy, Mohamed M; Mason, Claire E; Urathamakul, Thitima; Ozawa, Kiyoshi; Robinson, Andrew; Goudsmits, Joris MH; Wang, Yao; Pan, Xuefeng; Beck, Jennifer; van Oijen, Antoine M; Huber, Thomas; Hamdan, Samir; Dixon, Nicholas Edward

Description

Processive DNA synthesis by the αÉ"θ core of the Escherichia coli Pol III replicase requires it to be bound to the β 2 clamp via a site in the α polymerase subunit. How the É" proofreading exonuclease subunit influences DNA synthesis by α was not p

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
URI: http://hdl.handle.net/1885/62001
Source: EMBO Journal, The
DOI: 10.1038/emboj.2012.347

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