Skip navigation
Skip navigation

Fimbricalyx A, a novel phenanthrenone derivative having a rare 2H-benz[e]inden-2-one substructure

Seephonkai, Prapairat; Pyne, Stephen G; Willis, Anthony; Lie, Wilford


Fimbricalyx A (1), a novel phenanthrenone derivative having a rare 2H-benz[e]inden-2-one substructure, was isolated from the root extract of Strophioblachia fimbricalyx. The structure of 1 was elucidated on the basis of the NMR and MS data and confirmed by X-ray crystallography. This compound showed cytotoxicity against KB, MCF7 and NCI-H187 cancer cells with IC50 values of 38.4, 28.7 and 8.3 μg/mL, respectively. A possible biosynthesis of 1, via a ring-contracted p-quinone methide intermediate...[Show more]

CollectionsANU Research Publications
Date published: 2013
Type: Journal article
Source: Tetrahedron Letters
DOI: 10.1016/j.tetlet.2013.02.025


File Description SizeFormat Image
01_Seephonkai_Fimbricalyx_A,_a_novel_2013.pdf596.68 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator