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PathExpress update: the enzyme neighbourhood method of associating gene-expression data with metabolic pathways

Goffard, Nicolas; Frickey, Tancred; Weiller, Georg


The post-genomic era presents us with the challenge of linking the vast amount of raw data obtained with transcriptomic and proteomic techniques to relevant biological pathways. We present an update of PathExpress, a web-based tool to interpret gene-expression data and explore the metabolic network without being restricted to predefined pathways. We define the Enzyme Neighbourhood (EN) as a sub-network of linked enzymes with a limited path length to identify the most relevant sub-networks...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Nucleic Acids Research
DOI: 10.1093/nar/gkp432


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