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Strains of Epstein-Barr virus infecting multiple sclerosis patients

Brennan, R M; Burrows, J M; Bell, M J; Bromham, Lindell; Csurhes, P A; Lenarczyk, A; Sverndal, J; Klintenstedt, J; Pender, M P; Burrows, Scott

Description

Both epidemiological and experimental studies have indicated that the ubiquitous herpesvirus Epstein-Barr virus (EBV) plays a role in the pathogenesis of multiple sclerosis (MS). Some features of MS epidemiology, such as the decline in risk among migrants from high to low MS prevalence areas, suggest the presence of variant EBV strains that increase MS risk. The objective of this study was to investigate whether genetic variability in EBV is associated with MS. Genes encoding for two EBV...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/61634
Source: Multiple Sclerosis
DOI: 10.1177/1352458510364537

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