Skip navigation
Skip navigation

Life history of cones in the Rhodopsin-Mutant P23H-3 rat: Evidence of long-term survival

Chrysostomou, Vicki; Stone, Jonathan; Valter (Valter-Kocsi), Krisztina


PURPOSE. To follow the status of cones over the life of the P23H-3 transgenic rat, while the rod population is depleted. METHODS. P23H-3 heterozygous and Sprague-Dawley (SD) control rats were raised in dim, cyclic light from postnatal day (P)10 to P540. Retinas were examined for cone density, cone outer segment (OS) length, cone axon and soma morphology, and the amplitude of rod and cone components of the electro-retinogram (ERG) were determined. RESULTS. In the P23H-3 retina, cone density...[Show more]

CollectionsANU Research Publications
Date published: 2009
Type: Journal article
Source: Investigative Ophthalmology and Visual Science
DOI: 10.1167/iovs.08-3003


File Description SizeFormat Image
01_Chrysostomou_Life_history_of_cones_in_the_2009.pdf758.78 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  12 November 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator