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Cofactor promiscuity among F 420 -dependent reductases enables them to catalyse both oxidation and reduction of the same substrate

Lapalikar, Gauri V; Taylor, Matthew C; Warden, Andrew C; Onagi, Hideki; Hennessy, James E; Mulder, Roger J; Scott, Colin; Brown, Susan E; Russell, Robyn J; Easton, Christopher; Oakeshott , John

Description

The recently reported F420H2-dependent reductases (FDRs) catalyse the reduction of aflatoxins and coumarin via hydrogenation of the α,β-unsaturated moiety. We report that three FDRs (MSMEG-2027, MSMEG-6848 and MSMEG-3356) from Mycobacterium smegmatis al

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/61579
Source: Catalysis Science and Technology
DOI: 10.1039/c2cy20129a

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