Skip navigation
Skip navigation

Approaches to the neurotrophically active natural product 11-O-debenzoyltashironin: a chemoenzymatic total synthesis of the structurally related sesquiterpene khusiol

Sharma, Mukesh; Banwell, Martin; Willis, Anthony; Rae, A David

Description

Soothes your nerves: The enantiomerically enriched cis-1,2-dihydrocatechol 4 has been converted, over 16 steps including one involving an intramolecular Diels-Alder reaction, into the sesquiterpenoid natural product khusiol (3), which is structurally related to the neurite outgrowth-promoting natural product 11-O-debenzoyltashironin (1).

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/61434
Source: Chemistry - An Asian Journal
DOI: 10.1002/asia.201100913

Download

File Description SizeFormat Image
01_Sharma_Approaches_to_the_2012.pdf237.9 kBAdobe PDF    Request a copy


Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  23 August 2018/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator