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Comparison of dermal absorption of zinc from different sunscreen formulations and differing UV exposure based on stable isotope tracing

Gulson, Brian; Wong, Herbert; Korsch, Michael; Gomez, Laura; Casey, Philip; McCall, Maxine; McCulloch, Malcolm; Trotter, Julie; Stauber, Jenny; Greenoak, Gavin

Description

In a pilot study to determine if zinc (Zn) from zinc oxide nanoparticles in sunscreen can penetrate human skin in vivo, nanoparticles (~30nm) of a stable isotope (52% 68Zn enrichment) were incorporated into an essentially phytochemical-based formulation and applied to the backs of 3 human subjects twice daily for 5days during the Southern Hemisphere winter. Blood and urine were collected prior to application and at regular intervals and up to 50days. As observed in a larger outdoor trial...[Show more]

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
URI: http://hdl.handle.net/1885/61334
Source: Science of the Total Environment
DOI: 10.1016/j.scitotenv.2011.12.046

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