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Characterization of TCTP, the translationally controlled tumor protein, from Arabidopsis thaliana

Berkowitz, Oliver; Jost, Ricarda; Pollmann, Stephan; Masle, Josette

Description

The translationally controlled tumor protein (TCTP) is an important component of the TOR (target of rapamycin) signaling pathway, the major regulator of cell growth in animals and fungi. TCTP acts as the guanine nucleotide exchange factor of the Ras GTPase Rheb that controls TOR activity in Drosophila melanogaster. We therefore examined the role of Arabidopsis thaliana TCTP in planta. Plant TCTPs exhibit distinct sequence differences from nonplant homologs but share the key GTPase binding...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/61095
Source: The Plant Cell
DOI: 10.1105/tpc.108.061010

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