Skip navigation
Skip navigation

Cell division requires a direct link between microtubule-bound RacGAP and Anillin in the contractile ring

Gregory, Stephen L; Ebrahimi, Saman; Milverton, Joanne; Jones, Whitney M; Bejsovec, Amy; Saint, Robert


The mitotic microtubule array plays two primary roles in cell division. It acts as a scaffold for the congression and separation of chromosomes, and it specifies and maintains the contractile-ring position. The current model for initiation of Drosophila and mammalian cytokinesis [1-5] postulates that equatorial localization of a RhoGEF (Pbl/Ect2) by a microtubule-associated motor protein complex creates a band of activated RhoA [6], which subsequently recruits contractile-ring components such...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
Source: Current Biology
DOI: 10.1016/j.cub.2007.11.050


File Description SizeFormat Image
01_Gregory_Cell_division_requires_a_2008.pdf820.97 kBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  19 May 2020/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator