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The genome of the model beetle and pest Tribolium castaneum

Richards, Stephen; Gibbs, R A; Weinstock, G M; Brown, Susan J; Denell, Robin; Beeman, Richard W; Bucher, Gregor; Friedrich, Markus; Grimmelikhuijzen, Cornelius J P; Klinger, Martin; Foret, Sylvain; Maleszka, Ryszard

Description

Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more...[Show more]

dc.contributor.authorRichards, Stephen
dc.contributor.authorGibbs, R A
dc.contributor.authorWeinstock, G M
dc.contributor.authorBrown, Susan J
dc.contributor.authorDenell, Robin
dc.contributor.authorBeeman, Richard W
dc.contributor.authorBucher, Gregor
dc.contributor.authorFriedrich, Markus
dc.contributor.authorGrimmelikhuijzen, Cornelius J P
dc.contributor.authorKlinger, Martin
dc.contributor.authorForet, Sylvain
dc.contributor.authorMaleszka, Ryszard
dc.date.accessioned2015-12-10T22:58:10Z
dc.identifier.issn0028-0836
dc.identifier.urihttp://hdl.handle.net/1885/60735
dc.description.abstractTribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell-cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneum functions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.
dc.publisherMacmillan Publishers Ltd
dc.sourceNature
dc.subjectKeywords: cysteine; cytochrome P450; G protein coupled receptor; neurohormone; beetle; detoxification; fly; genome; identification method; pest control; pest species; species richness; article; beetle; Caenorhabditis elegans; cell communication; chemical environmen
dc.titleThe genome of the model beetle and pest Tribolium castaneum
dc.typeJournal article
local.description.notesImported from ARIES
local.identifier.citationvolume452
dc.date.issued2008
local.identifier.absfor060408 - Genomics
local.identifier.absfor060407 - Genome Structure and Regulation
local.identifier.ariespublicationu9204316xPUB559
local.type.statusPublished Version
local.contributor.affiliationRichards, Stephen, Baylor College of Medicine
local.contributor.affiliationGibbs, R A, Baylor College of Medicine
local.contributor.affiliationWeinstock, G M, Baylor College of Medicine
local.contributor.affiliationBrown, Susan J, Kansas State University
local.contributor.affiliationDenell, Robin, Kansas State University
local.contributor.affiliationBeeman, Richard W, United States Dept of Agriculture
local.contributor.affiliationBucher, Gregor, Georg-August University
local.contributor.affiliationFriedrich, Markus, Wayne State University
local.contributor.affiliationGrimmelikhuijzen, Cornelius J P, University of Copenhagen
local.contributor.affiliationKlinger, Martin, Friedrich Alexander University
local.contributor.affiliationForet, Sylvain, College of Medicine, Biology and Environment, ANU
local.contributor.affiliationMaleszka, Ryszard, College of Medicine, Biology and Environment, ANU
local.description.embargo2037-12-31
local.bibliographicCitation.startpage949
local.bibliographicCitation.lastpage955
local.identifier.doi10.1038/nature06784
dc.date.updated2015-12-10T08:04:14Z
local.identifier.scopusID2-s2.0-41949090434
local.identifier.thomsonID000255208600030
CollectionsANU Research Publications

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