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3-Mercapto-1,2,4-triazoles and N-acylated thiosemicarbazides as metallo-β-lactamase inhibitors

Faridoon, Mr; Hussein, Waleed M; Vella, Peter; Ul Islam, Nazar; Ollis, David; Schenk, Gerhard; McGeary, Ross Peter


The production of β-lactamases is an effective strategy by which pathogenic bacteria can develop resistance against β-lactam antibiotics. While inhibitors of serine-β-lactamases are widely used in combination therapy with β-lactam antibiotics, there a

CollectionsANU Research Publications
Date published: 2012
Type: Journal article
Source: Bioorganic and Medicinal Chemistry Letters
DOI: 10.1016/j.bmcl.2011.10.116


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