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Antimicrobial peptide immunity protects human nasal and auricular cartilage against infection

Warnke, Patrick H.; Russo, Paul; Hopfenziz, Martin; Kurz, Bodo; Becker, Stephan T; Sherry, Eugene; Springer, Ingo; Sivananthan, Sureshan

Description

Background: Despite being impervious to surveillance by the adaptive immune system because of its lack of vascularity, infection of the nasal and auricular cartilage after surgery such as rhinoplasty or otoplasty is rare. Why is this so? Our goal was to determine whether the expression of antimicrobial peptides provides a previously unrecognized nonepithelial layer of innate immune defense within the nasal and auricular cartilage. Materials and Methods: Seven samples of nasal septum cartilage...[Show more]

CollectionsANU Research Publications
Date published: 2010
Type: Journal article
URI: http://hdl.handle.net/1885/60532
Source: Journal of Craniofacial Surgery
DOI: 10.1097/SCS.0b013e3181c50fc2

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