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Line-1 Elements: Analysis by Fluorescence In-Situ Hybridization and Nucleotide Sequences

Waters, Paul; Dobigny, Gauthier; Waddell, Peter J; Robinson, Terence J

Description

Long-interspersed nuclear element-1 (LINE-1) is a non-terminal repeat transposon that constitutes a major component of the mammalian genome. LINE-1 has a dynamic evolutionary history characterized by the rise, fall, and replacement of subfamilies. The distribution of LINE-1 elements can be viewed from a chromosomal perspective using fluorescence in-situ hybridization (FISH), as well as at the sequence level. We have designed LINE-1 primers from regions conserved among mouse, rat, rabbit, and...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Book chapter
URI: http://hdl.handle.net/1885/60467

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