Gao, Ling-Juan; Ding, Lan; Guo, Shu-Yu; Cai, You-Qun; Su, Ya-Juan; Gong, Hui; Liu, Yun; Chen, Chen; Gu, Ping-Qing
Background: Decay-accelerating factor (DAF) is one of the key molecules involved in cell protection against autologous complement, which restricts the action of complement at critical stages of the cascade reaction. The effect of DAF on the survival of human cervical cancer cell (ME180) has not been demonstrated. Methods: In this study we applied, for the first time, small interference RNA (siRNA) to knock down the expression of the DAF with the aim of exploiting complement more effectively for...[Show more]
Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.