Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis
Background and aims:The serum/plasma proteome was explored for biomarkers to improve the diagnostic ability of CA19-9 in pancreatic adenocarcinoma (PC).Methods:A Training Set of serum samples from 20 resectable and 18 stage IV PC patients, 54 disease controls (DCs) and 68 healthy volunteers (HVs) were analysed by surface-enhanced laser desorption and ionisation time-of-flight mass spectrometry (SELDI-TOF MS). The resulting protein panel was validated on 40 resectable PC, 21 DC and 19 HV plasma...[Show more]
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|Source:||British Journal of Cancer|
|01_Xue_Discovery_of_serum_biomarkers_2010.pdf||773.2 kB||Adobe PDF||Request a copy|
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