Wolfle, Stephanie; Chaston, Daniel; Goto, Kenichi; Sandow, Shaun, L; Edwards, Frank; Hill, Caryl
Blood flow is adjusted to tissue demand through rapidly ascending vasodilatations resulting from conduction of hyperpolarisation through vascular gap junctions. We investigated how these dilatations can spread without attenuation if mediated by an electrical signal. Cremaster muscle arterioles were studied in vivo by simultaneously measuring membrane potential and vessel diameter. Focal application of acetylcholine elicited hyperpolarisations which decayed passively with distance from the local...[Show more]
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