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Exploring the Enzyme Neighbourhood to interpret gene expression data

Goffard, Nicolas; Frickey, Tancred; Imin, Nijat; Weiller, Georg

Description

Post-genomic data analysis represents a new challenge to link and interpret the vast amount of raw data obtained with transcriptomic or proteomic techniques in the context of metabolic pathways. We propose a new strategy with the help of a metabolic network graph to extend PathExpress, a web-based tool to interpret gene expression data, without being restricted to predefined pathways. We defined the Enzyme Neighbourhood as groups of linked enzymes, corresponding to a sub-network, to explore the...[Show more]

CollectionsANU Research Publications
Date published: 2008
Type: Book chapter
URI: http://hdl.handle.net/1885/59820

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