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Role of the Transcription Factor Sox4 in Insulin Secretion and Impaired Glucose Tolerance

Goldsworthy, Michelle; Hugill, Alison; Freeman, Helen; Horner, Emma; Shimomura, Kenju; Bogani, Debora; Pieles, Guido; Mijat, Vesna; Arkell, Ruth; Bhattacharya, Shoumo; Ashcroft, Frances M; Cox, Roger D

Description

OBJECTIVES-To identify, map, clone, and functionally validate a novel mouse model for impaired glucose tolerance and insulin secretion. RESEARCH DESIGN AND METHODS-Haploinsufflciency of the insulin receptor and associated mild insulin resistance has been

CollectionsANU Research Publications
Date published: 2008
Type: Journal article
URI: http://hdl.handle.net/1885/59461
Source: Diabetes
DOI: 10.2337/db07-0337

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