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Potent and selective inhibitors of human peptidylglycine α-amidating monooxygenase

Cao, Feihua (Lucy); Gamble, Allan; Kim, Hye-Kyung; Onagi, Hideki; Gresser, Mary; Kerr, Jamie; Easton, Christopher

Description

Fatty acid glycolates are nanomolar inhibitors of small cell lung carcinoma peptidylglycine α-amidating monooxygenase, with binding affinities orders of magnitude stronger than those of the analogous thioesters, the corresponding substrate glycine deriva

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
URI: http://hdl.handle.net/1885/59329
Source: MedChemComm
DOI: 10.1039/c1md00079a

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