Skip navigation
Skip navigation

Engineering of a bis-chelator motif into a protein α-helix for rigid lanthanide binding and paramagnetic NMR spectroscopy

Swarbrick, James; Ung, Phuc; Su, Xun-Cheng; Maleckis, Ansis; Chhabra, Sandeep; Graham, Bim; Otting, Gottfried; Huber, Thomas


Attachment of two nitrilotriacetic acid-based ligands to a protein α-helix in an i, i + 4 configuration produces an octadentate chelating motif that is able to bind paramagnetic lanthanide ions rigidly and with high affinity, leading to large pseudoconta

CollectionsANU Research Publications
Date published: 2011
Type: Journal article
Source: Chemical Communications
DOI: 10.1039/c1cc11893e


File Description SizeFormat Image
01_Swarbrick_Engineering_of_a_bis-chelator_2011.pdf1.24 MBAdobe PDF    Request a copy

Items in Open Research are protected by copyright, with all rights reserved, unless otherwise indicated.

Updated:  17 November 2022/ Responsible Officer:  University Librarian/ Page Contact:  Library Systems & Web Coordinator